运动表现研究

Circulating mitochondrial-derived microproteins at rest and in response to an acute bout of endurance exercise in individuals with cerebral palsy

Experimental Physiology · 典型发育成人、典型发育青少年和脑瘫成人（GMFCS II-IV）；急性耐力运动

MOTS-c improves intrinsic muscle mitochondrial bioenergetic health and efficiency in a PGC-1α/AMPK-dependent manner

Free Radical Biology and Medicine · 两个转基因小鼠品系（PGC-1alpha 和 AMPK 模型）给予 MOTS-c；骨骼肌线粒体生物能学

Reduced serum and skeletal muscle MOTS c levels in women with polycystic ovary syndrome are associated with mitochondrial dysfunction

Scientific Reports · 40 名多囊卵巢综合征女性与 40 名年龄和 BMI 匹配的对照；血清和骨骼肌采样

Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance

Sports Medicine · 体育医学中使用的获批和未获批肽的叙述性综述，包括线粒体来源肽

Systemic MOTS-c levels are increased in adults with obesity in association with metabolic dysregulation and remain unchanged after weight loss

Journal of Clinical & Translational Endocrinology · 22 名瘦型和 32 名肥胖成人的横断面比较，其中 10 名在减肥手术后随访

A phase-II randomized controlled pilot study of nicotinamide riboside supplementation in older adults with amnestic mild cognitive impairment

Alzheimer's & Dementia · 12周 II 期双盲随机安慰剂对照先导试验，42名患有遗忘型轻度认知障碍的老年人（NR 组 n = 22，安慰剂组 n = 20）

Low-dose oral nicotinamide mononucleotide for immune thrombocytopenia: a phase 1/2 trial

Nature Medicine · 单臂开放标签 1/2 期试验，25名激素难治性或激素依赖性免疫性血小板减少症成人患者，NMN 450 mg 每日两次，持续2周，并有小鼠巨噬细胞支持性实验

Safety and efficacy of individualised exercise and NAD+ precursor supplementation in patients with Friedreich's ataxia in the USA: a single-centre, 2 × 2 factorial, randomised controlled trial

The Lancet Neurology · 2期单中心2×2析因随机对照试验，66名年龄10-40岁的Friedreich共济失调患者，12周基于体重的烟酰胺核糖苷（300-900 mg）和/或个性化家庭运动